Influence of Repressive Histone and DNA Methylation upon D4Z4 Transcription in Non-Myogenic Cells
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منابع مشابه
Influence of Repressive Histone and DNA Methylation upon D4Z4 Transcription in Non-Myogenic Cells
We looked at a disease-associated macrosatellite array D4Z4 and focused on epigenetic factors influencing its chromatin state outside of the disease-context. We used the HCT116 cell line that contains the non-canonical polyadenylation (poly-A) signal required to stabilize somatic transcripts of the human double homeobox gene DUX4, encoded from D4Z4. In HCT116, D4Z4 is packaged into constitutive...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2016
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0160022